CVRG
CardioVascular Research Grid (CVRG): A Distributed Community Resource for Multi-Scale Cardiovascular Data Integration Discovery
- funding agency: John Hopkins University
- date: 03/2007 - 01/2011
- grant amount: $1,941,544.00
- Research on the systems biology of cardiovascular disease offers great potential to improve our understanding of the disease mechanism at multiple scales of biological organization, from genes to cells to tissues to the whole organ. It also can enhance our ability to discover new biological markers that can be used to diagnose disease risk for individuals, assess disease state, and identify risk groups. Efforts of cardiovascular researchers are, however, limited by the lack of infrastructure to support collaborative efforts, integrate multi-scale data obtained from cardiovascular research and clinical studies, and share analysis tools. This project will create an innovative resource, the CardioVascular Research Grid (CVRG), to facilitate and promote research efforts that span multiple research groups and institutions. The CVRG will provide the cardiovascular research community an open-source, extensible software infrastructure enabling discovery, federation, and sharing of cardiovascular data and tools. It will also provide community access to novel tools for the discovery of biomarkers. The CVRG is an inter-disciplinary, collaborative effort, bringing together biomedical and software systems researchers at Johns Hopkins University, the Ohio State University, and University of California at San Diego. The Biomedical Informatics Department (BMI) of OSU is leading the effort to build the core Grid middleware infrastructure to support CVRG functions. The design and implementation of this core middleware infrastructure will leverage software systems developed by BMI, the cancer Biomedical Informatics Grid (caBIGTM) caGrid infrastructure, and software infrastructure from the Biomedical Informatics Research Grid (BIRN).
- Project Investigators:
- Joel Saltz, M.D., Ph.D. (PI)
- Tahsin Kurc, Ph.D. (PI)
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